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Science Behind SoME™

Aesthetics Biomedical Inc. has launched a personalized topical product line for take-home use. SoME™ the lead product is a skin rejuvenating treatment that uses a propriety blend of ingredients to formulate a specialized serum. SoME is combined with your own Platelet Rich Plasma (PRP), by your physician, to give you a truly personalized cosmetic experience.


Autologous Additive
Platelet Rich Plasma (PRP)

PRP has gained momentum over the years for orthopedic applications with an increased interest in the application of wound healing. The use of PRP in aesthetics has grown and inspired the development of the take-home cosmetic formulation SoME™. PRP comes from your very own whole blood and is obtained from a process called centrifugation. PRP has many cell components and factors that have shown potential for skin rejuvenation. The growth factors within PRP are Platelet Derived Growth Factors (PDGFaa, PDGFbb, and PDGFab), transforming growth factor beta (TGF-B1, 2), epithelial growth factor (EGF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and connected tissue growth factor (CTGF).

Novel Skin Nutrient System/Complex
Glucose (D), Sodium Chloride, Sodium Citrate, Sodium Acetate, Sodium Bicarbonate, Potassium Phosphate, Potassium Chloride, Magnesium Chloride
Botanical Preservative System
Lonicera Japonica (Honeysuckle) Flower Extract, Lonicera Caprifolium (Honeysuckle) Flower Extract
Botanical and Antioxidant Complexes
Persea Gratissima (Avocado) Oil, Althaea Officinalis (Marshmallow) Root Extract, Tocopheryl Acetate (D-alpha)
Specialty Ingredients
Sodium Hyaluronate (Low molecular weight HA)

Novel Skin Care System:

This next generation skin care system that incorporates an individual’s autologous PRP is perfect for all skin types because it is all you. The SoME™ serum, that preserves the PRP does not contain any of the harsh and unnatural alcohols that typical skin care products use such as phenoxyethanol, benzyl alcohol, and other denatured alcohols that are known to dehydrate and dry out the skin. SoME™ uses a botanical preservative package, two honeysuckle variants (Lonicera Japonica, Lonicera Caprifolium), to keep SoME™ from degrading and keep it fresh for your everyday use. SoME™ also utilizes a novel skin nutrient system that includes glucose, sodium variants, potassium variants, and magnesium variants to give your skin the nutrients needed to keep fresh and healthy during day and night. All ingredients in SoME™ we carefully selected to provide the best, personalized, cosmetic experience.

Proven Clinical Data


Over time your skin will show signs of aging as your collagen and elastin production decreases naturally as you age. In a randomized blind split-face study, SoME™ base and SoME™ base + PRP were tested to show the significant improvement when the SoME™ base had the PRP additive. SoME™ showed that when used on the face twice a day over a short 8 weeks that it can moisturize and help visibly improve skin texture and tone, firmness, luminosity, and provide a softer, smoother, more radiant look. Therefore SoME™ is a perfect supplement to incorporate into your daily skin care routine to combat the visible signs of aging and photodamaged skin. The study included patient skin biopsies so that histologic staining and qPCR could be used to evaluate important markers within the skin. The results showed SoME™ base + PRP to significantly improve collagen (Fig. 1), elastin (Fig. 2), and rete peg (Fig. 3). Confirming that a personalized cosmetic can effectively combat the visible signs of facial aging, creating the appearance of a more youthful self.

Figure 1: Collagen I Analysis uses color deconvolution algorithms to determine the staining intensity of the DAB color for Collagen I. The Left panel (blue border) is the treatment sample (3R) the Right panel (orange Border) is the control sample (3L). False color mark-up of the image yellow = weak positive, orange = positive, red = highly positive, blue = negative. Scale bars = 200 µm.

Figure 2: Elastin Analysis uses color deconvolution algorithms to determine the staining intensity of the DAB color for Elastin. The Left panel (blue border) is the treatment sample (2L) the Right panel (orange Border) is the control sample (2R). False color mark-up of the image yellow = weak positive, orange = positive, red = highly positive, blue = negative. Scale bars = 200 µm.

Figure 3: Rete Peg analysis is a ratio of the stratum basale to the stratum granulosum, the red line traces the dermal-epidermal junction, the wavier the line, the healthier the skin. The higher the number, the more rete pegs are present. The upper panel (orange border) is the control sample (2R) the lower panel (blue Border) is the treatment sample (2L). Scale bars = 100 µm.

Before & After Images


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Baseline vs. 12 Weeks, Female, Age 69, Fitz ll
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  • 98%

    of Patients
  • 2

Our Patient Satisfaction

A 60-day, 20 subject split face, blinded study demonstrated enhanced softness, brightness, luminosity, firmness at four weeks with a more robust performance at eight weeks, as assessed by both the investigator and study patients. At four weeks 98% of patients demonstrated that when applied twice daily (morning and evening), SoME™ + PRP* provided visible changes to the skin.

Keep up to date about SoME™ products

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Keep up to date about SoME™ products

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Disclaimer:
Aesthetics Biomedical’s SoME™ products described on this website are intended to meet the FDA’s definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These Aesthetics Biomedical products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA and the statements on these pages have not been evaluated by the FDA.
Before and After Photos – individual results may vary. Some images may be models

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